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Syphilis
Treponema pallidum
Primary, secondary, or early latent (asymptomatic <1 year) syphilis:
Benzathine Penicillin G 50,000U/kg (max 2.4 million units) IM single dose¹
Late latent syphilis (asymptomatic >1 year or unknown duration of infection):
Benzathine Penicillin G 50,000U/kg (max 2.4 million units) IM weekly for 3 doses¹
Empiric Therapy & Alternative Regimens
Duration of Therapy & Clinical Pearls
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