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Periorbital/Preseptal Cellulitis
MSSA/MRSA, S. pyogenes,
S. pneumoniae, H. influenzae (type B, non-typeable), M. catarrhalis
Clindamycin 30 mg/kg/day PO/IV div q8h (max 600mg/dose)¹
If no MRSA risk factors (no contact sports, daycare, exposure to healthcare facilities, or family history), can consider discharge home with Cephalexin 100mg/kg/day instead of Clindamycin
Empiric Therapy & Alternative Regimens
Duration of Therapy & Clinical Pearls
Consider periorbital cellulitis in those cases with erythema and edema of the eyelid WITHOUT ocular pain or pain with extraocular movements.
Can initiate therapy with PO therapy in non-severe cases. If requiring IV therapy, transition to PO once afebrile and clinically improved.¹ ³
Length of Therapy:
7-10 days¹
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